Psychosis: 15% Likelihood of remaining relapse free at 15 years
Clinical Bottom Line
Patients with first episode non-affective functional psychosis have a 15% likelihood of remaining free from relapse over 15 years
Wiersma, D, Nienhuis, FJ, Slooff, C.J. and Giel R. Natural course of schizophrenic disorders: a 15-year followup of a Dutch incidence cohort. Schizophr.Bull. 24 (1):75-85, 1998.
In a patient with first episode functional psychosis, what is the likelihood of remaining free from relapse in the long term?
hand search Evidence-Based Mental Health
Long term follow up of first-contact cases of non-affective functional psychosis from a geographically defined region in the Netherlands. At 6 months, 63% had DSM-IIIR schizophrenia or schizophreniform disorder. Explicit criteria were used for determining relapse. Data collection was standardised although much was retrospective from casenotes and informants.
|Relapse-free following remission of first episode||1 year||57%||Not calculable|
|2 years||45%||Not calculable|
|5 years||70%||Not calculable|
|15 years||15%||7 to 22%|
Commentary in Evidence-Based Mental Health includes extra information that was obtained from authors