Stroke-risk of seizure
Clinical Bottom Line
Acute Cholecystitis - Lap chole may be as safe as open chole
Citation
Burn J, Dennis M, Bamford J et al. Epileptic seizures after a first stroke: the Oxfordshire community stroke project. BMJ 1997;315:1582-7
Clinical Question
In a patient with stroke, what is the risk of seizure at one year?
Search Terms
"stroke" and "seizure" in Medline
The Study
- 675 pts registered in a community-based stroke registry after their first stroke
- The Outcome: seizure
- Well-defined sample at uniform (early) stage of illness..?, yes;
- Follow-up long enough..?, yes;
- Follow-up complete..?, yes;
- Blind and objective outcome criteria..?, no;
- Adjustment for other prognostic factors..?, no;
- Validation in an independent "test-set" of patients..?, no
The Evidence
| Prognostic Factor | Outcome | Time | Measure | Likelihood Ratio |
|---|---|---|---|---|
| cerebral infarction | seizure | 1 year | 4.2% | 2.2 to 6.2% |
| primary intracerebral haemorrhage | seizure | 1 year | 20% | 1.5 to 38.3% |
| subarachnoid haemorrhage | seizure | 1 year | 22% | 2.6 to 41.8% |
| any stroke | seizure | 1 year | 5.7% | 3.5 to 7.9% |
Appraised By
Straus, 1998
Expiry Date
2000