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Centre for Evidence-
Based Medicine

Acute Cholecystitis - Lap chole may be as safe as open chole

Clinical Bottom Line

Acute Cholecystitis - Lap chole may be as safe as open chole


Kiviluoto T, Siren J, Luukkonen P & Kivilaakso E. Randomised trial of laparoscopic versus open cholecystectomy for acute and gangrenous cholecystitis. Lancet 1998; 351: 321-5.

Clinical Question

In patients with acute cholecystectomy, what is the complication rate of laparascopic cholecystectomy versus open cholecystectomy?

Search Terms

laparascopic cholecystectomy and open cholecystectomy and cholecystitis in Medline

The Study

  • Non-blinded randomised controlled trial without intention-to-treat.
  • The Study Patients: patients with acute cholecystitis
  • Control group (N = 31; analysed): open cholecystectomy
  • Experimental group (N = 32; analysed): lap chole

The Evidence

Complication from surgery 42% 3% 93% .39 (2 to 5)
Complication including conversion to open chole 42% 19% 55% .23 4 (2 to 106)


  1. small study
  2. lap chole carried out by experts while open chole mostly carried out by trainees

Expiry Date

Kill or Update by: 2001