Harm: Clinical Scenario
A 50 year old man asked for a repeat prescription of sotalol which he had been taking for several years for his extrasystoles. I had not previously seen him, and was cautious because of the number of antiarrhythmics which had proarrhythmic properties. I formulated the question, in patients with extrasystoles does sotalol increase the risk of sudden cardiac death?
Searching terms and evidence source: sotalol AND (mortality OR death*) - search done in the Cochrane Controlled Trials Registry
Read the article and decide:
- Is the evidence from this study valid?
- If valid, is this evidence important?
- If valid and important, can you apply this evidence in caring for your patient?