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Centre for Evidence-
Based Medicine

Critical Appraisal of Evidence

Tips on Critical Appraisal of Evidence

After we have searched for the evidence, we need to decide if it is both valid and important before deciding if we can apply the evidence to our individual patients. The order in which we consider validity and importance depends on individual preference.

Which type of evidence would you like to appraise?

Diagnosis
Elderly woman with possible iron deficiency anaemia
Prognosis
Man with a history of a stroke who is concerned about his risk of seizure
Therapy
Single trials - man with stroke, moderate carotid stenosis
Systematic review - man with a stroke who gets admitted to stroke unit
Harm
Man with extrasystoles on sotalol

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